The management of cancer-related fatigue after chemotherapy with acupuncture and acupressure: a randomised controlled trial

2.50
Hdl Handle:
http://hdl.handle.net/10541/70264
Title:
The management of cancer-related fatigue after chemotherapy with acupuncture and acupressure: a randomised controlled trial
Authors:
Molassiotis, Alexander; Sylt, Paola; Diggins, Helen
Abstract:
BACKGROUND: Cancer-related fatigue after chemotherapy is a difficult symptom to manage in practice and the most disruptive symptom in patients' lives. Acupuncture is a popular complementary therapy among cancer patients and some evidence exists that it could potentially alleviate fatigue by stimulating 'energy' points in the body. Hence, this study was carried out to assess the effects of acupuncture and acupressure in managing cancer-related fatigue and the feasibility of running a randomised trial with these two complementary therapies in preparation for a large trial. METHODS: This study was a randomised controlled trial. Forty-seven patients with cancer who experienced moderate to severe fatigue were randomised either to an acupuncture group (n=15), an acupressure group (n=16) or a sham acupressure group (n=16). The acupuncture group received six 20-min sessions over 2 weeks, while the patients in the two acupressure groups were taught to massage/press the points and did so daily thereafter for 2 weeks on their own. Patients completed the Multidimensional Fatigue Inventory before randomisation, at the end of the 2-week intervention and again about 2 weeks after the end of the intervention. RESULTS: Significant improvements were found with regards to General fatigue (P<0.001), Physical fatigue (P=0.016), Activity (p=0.004) and Motivation (P=0.024). At the end of the intervention, there was a 36% improvement in fatigue levels in the acupuncture group, while the acupressure group improved by 19% and the sham acupressure by 0.6%. Improvements were observed even 2 weeks after treatments, although they were lower (22%, 15%, 7%, respectively). Acupuncture was a more effective method than acupressure or sham acupressure. Subjects needed a longer treatment period to have more sustained results. The trial was methodologically feasible. CONCLUSION: Acupuncture shows great potential in the management of cancer-related fatigue. As a randomised trial with acupuncture is feasible and preliminary data shows significant improvements, it should be tested further using a large sample and a multicentre design.
Affiliation:
University of Manchester, School of Nursing, Midwifery & Social Work, Coupland III, Coupland Street, Manchester M13 9PL, UK. alex.molassiotis@manchester.ac.uk
Citation:
The management of cancer-related fatigue after chemotherapy with acupuncture and acupressure: a randomised controlled trial. 2007, 15 (4):228-37 Complement Ther Med
Journal:
Complementary Therapies in Medicine
Issue Date:
Dec-2007
URI:
http://hdl.handle.net/10541/70264
DOI:
10.1016/j.ctim.2006.09.009
PubMed ID:
18054724
Type:
Article
Language:
en
ISSN:
0965-2299
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorMolassiotis, Alexander-
dc.contributor.authorSylt, Paola-
dc.contributor.authorDiggins, Helen-
dc.date.accessioned2009-06-12T10:27:35Z-
dc.date.available2009-06-12T10:27:35Z-
dc.date.issued2007-12-
dc.identifier.citationThe management of cancer-related fatigue after chemotherapy with acupuncture and acupressure: a randomised controlled trial. 2007, 15 (4):228-37 Complement Ther Meden
dc.identifier.issn0965-2299-
dc.identifier.pmid18054724-
dc.identifier.doi10.1016/j.ctim.2006.09.009-
dc.identifier.urihttp://hdl.handle.net/10541/70264-
dc.description.abstractBACKGROUND: Cancer-related fatigue after chemotherapy is a difficult symptom to manage in practice and the most disruptive symptom in patients' lives. Acupuncture is a popular complementary therapy among cancer patients and some evidence exists that it could potentially alleviate fatigue by stimulating 'energy' points in the body. Hence, this study was carried out to assess the effects of acupuncture and acupressure in managing cancer-related fatigue and the feasibility of running a randomised trial with these two complementary therapies in preparation for a large trial. METHODS: This study was a randomised controlled trial. Forty-seven patients with cancer who experienced moderate to severe fatigue were randomised either to an acupuncture group (n=15), an acupressure group (n=16) or a sham acupressure group (n=16). The acupuncture group received six 20-min sessions over 2 weeks, while the patients in the two acupressure groups were taught to massage/press the points and did so daily thereafter for 2 weeks on their own. Patients completed the Multidimensional Fatigue Inventory before randomisation, at the end of the 2-week intervention and again about 2 weeks after the end of the intervention. RESULTS: Significant improvements were found with regards to General fatigue (P<0.001), Physical fatigue (P=0.016), Activity (p=0.004) and Motivation (P=0.024). At the end of the intervention, there was a 36% improvement in fatigue levels in the acupuncture group, while the acupressure group improved by 19% and the sham acupressure by 0.6%. Improvements were observed even 2 weeks after treatments, although they were lower (22%, 15%, 7%, respectively). Acupuncture was a more effective method than acupressure or sham acupressure. Subjects needed a longer treatment period to have more sustained results. The trial was methodologically feasible. CONCLUSION: Acupuncture shows great potential in the management of cancer-related fatigue. As a randomised trial with acupuncture is feasible and preliminary data shows significant improvements, it should be tested further using a large sample and a multicentre design.en
dc.language.isoenen
dc.subjectCanceren
dc.subject.meshAcupressure-
dc.subject.meshAcupuncture Points-
dc.subject.meshAcupuncture Therapy-
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshAntineoplastic Agents-
dc.subject.meshFatigue-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshNeoplasms-
dc.subject.meshPilot Projects-
dc.subject.meshResearch Design-
dc.subject.meshTreatment Outcome-
dc.subject.meshUnited States-
dc.titleThe management of cancer-related fatigue after chemotherapy with acupuncture and acupressure: a randomised controlled trialen
dc.typeArticleen
dc.contributor.departmentUniversity of Manchester, School of Nursing, Midwifery & Social Work, Coupland III, Coupland Street, Manchester M13 9PL, UK. alex.molassiotis@manchester.ac.uken
dc.identifier.journalComplementary Therapies in Medicineen

Related articles on PubMed

All Items in Christie are protected by copyright, with all rights reserved, unless otherwise indicated.