Older women with operable breast cancer are less likely to have surgery.

2.50
Hdl Handle:
http://hdl.handle.net/10541/70059
Title:
Older women with operable breast cancer are less likely to have surgery.
Authors:
Lavelle, K; Moran, Anthony; Howell, Anthony ( 0000-0002-3879-5991 ) ; Bundred, Nigel J; Campbell, Malcolm; Todd, Chris
Abstract:
BACKGROUND: Older women are less likely to receive standard management for breast cancer than younger postmenopausal women. Whether differences in general health explain variations in the rates of surgery is not known. METHODS: In this prospective cohort study, 76 women aged 65 years or more attending breast units in Greater Manchester completed a survey measuring functional status (Elderly Population Health Status Survey's Activity of Daily Living), generic health status (Short Form 12) and health-related quality of life (European Organization for Research on Treatment of Cancer Quality of Life Questionnaire C30). Case-note review assessed co-morbidity (Charlson Index) and management. Primary surgery for operable breast cancer was investigated using logistic regression. RESULTS: A Charlson Index of 1 or more did not predict the use of surgery (P = 0.363). However, for each point increase on the 1-4 scale indicating worsening functional status, the odds of having surgery decreased by 16 times (odds ratio 0.063). The odds of a woman of 80 years or more having surgery decreased by a factor of 44 (odds ratio 0.023) compared with women aged 65-79 years, accounting for co-morbidity, functional status, pretreatment stage, social deprivation and type of hospital. CONCLUSION: Older women were less likely to have surgery for operable breast cancer than younger women, even after accounting for differences in general health and co-morbidity.
Affiliation:
School of Nursing, Midwifery and Social Work, University of Manchester, Withington Hospital, Manchester, UK. katrina.j.lavelle@manchester.ac.uk
Citation:
Older women with operable breast cancer are less likely to have surgery. 2007, 94 (10):1209-15 Br J Surg
Journal:
The British Journal of Surgery
Issue Date:
Oct-2007
URI:
http://hdl.handle.net/10541/70059
DOI:
10.1002/bjs.5834
PubMed ID:
17590857
Type:
Article
Language:
en
ISSN:
1365-2168
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorLavelle, K-
dc.contributor.authorMoran, Anthony-
dc.contributor.authorHowell, Anthony-
dc.contributor.authorBundred, Nigel J-
dc.contributor.authorCampbell, Malcolm-
dc.contributor.authorTodd, Chris-
dc.date.accessioned2009-06-09T16:53:19Z-
dc.date.available2009-06-09T16:53:19Z-
dc.date.issued2007-10-
dc.identifier.citationOlder women with operable breast cancer are less likely to have surgery. 2007, 94 (10):1209-15 Br J Surgen
dc.identifier.issn1365-2168-
dc.identifier.pmid17590857-
dc.identifier.doi10.1002/bjs.5834-
dc.identifier.urihttp://hdl.handle.net/10541/70059-
dc.description.abstractBACKGROUND: Older women are less likely to receive standard management for breast cancer than younger postmenopausal women. Whether differences in general health explain variations in the rates of surgery is not known. METHODS: In this prospective cohort study, 76 women aged 65 years or more attending breast units in Greater Manchester completed a survey measuring functional status (Elderly Population Health Status Survey's Activity of Daily Living), generic health status (Short Form 12) and health-related quality of life (European Organization for Research on Treatment of Cancer Quality of Life Questionnaire C30). Case-note review assessed co-morbidity (Charlson Index) and management. Primary surgery for operable breast cancer was investigated using logistic regression. RESULTS: A Charlson Index of 1 or more did not predict the use of surgery (P = 0.363). However, for each point increase on the 1-4 scale indicating worsening functional status, the odds of having surgery decreased by 16 times (odds ratio 0.063). The odds of a woman of 80 years or more having surgery decreased by a factor of 44 (odds ratio 0.023) compared with women aged 65-79 years, accounting for co-morbidity, functional status, pretreatment stage, social deprivation and type of hospital. CONCLUSION: Older women were less likely to have surgery for operable breast cancer than younger women, even after accounting for differences in general health and co-morbidity.en
dc.language.isoenen
dc.subjectBreast Canceren
dc.subject.meshAge Factors-
dc.subject.meshAged-
dc.subject.meshBreast Neoplasms-
dc.subject.meshCohort Studies-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshPatient Selection-
dc.subject.meshProspective Studies-
dc.titleOlder women with operable breast cancer are less likely to have surgery.en
dc.typeArticleen
dc.contributor.departmentSchool of Nursing, Midwifery and Social Work, University of Manchester, Withington Hospital, Manchester, UK. katrina.j.lavelle@manchester.ac.uken
dc.identifier.journalThe British Journal of Surgeryen

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