2.50
Hdl Handle:
http://hdl.handle.net/10541/69714
Title:
Normal testicular function and spermatogenesis.
Authors:
Shalet, Stephen M
Abstract:
The testis performs two basic functions, sperm production and testosterone secretion. Formation of the testis is genetically controlled; expression of the SRY gene directs the embryonic gonads into the pathway leading to the development of testes. By the fourth week of gestation in humans, the primordial germ cells derived from pluripotent cells of the embryonic epiblast proliferate and migrate from the endoderm of the yolk sac into the undifferentiated gonad, which becomes morphologically distinct during the seventh week of gestation in humans. Histological development of the testis is largely completed by the end of the third month of gestation. Pediatr Blood Cancer (c) 2009 Wiley-Liss, Inc.
Affiliation:
Department of Endocrinology, Christie Hospital, Manchester, England, UK.
Citation:
Normal testicular function and spermatogenesis. 2009: Pediatr Blood Cancer
Journal:
Pediatric Blood & Cancer
Issue Date:
2-Apr-2009
URI:
http://hdl.handle.net/10541/69714
DOI:
10.1002/pbc.22000
PubMed ID:
19343782
Type:
Article
Language:
en
ISSN:
1545-5017
Appears in Collections:
All Christie Publications ; Endocrinology

Full metadata record

DC FieldValue Language
dc.contributor.authorShalet, Stephen M-
dc.date.accessioned2009-06-04T09:26:09Z-
dc.date.available2009-06-04T09:26:09Z-
dc.date.issued2009-04-02-
dc.identifier.citationNormal testicular function and spermatogenesis. 2009: Pediatr Blood Canceren
dc.identifier.issn1545-5017-
dc.identifier.pmid19343782-
dc.identifier.doi10.1002/pbc.22000-
dc.identifier.urihttp://hdl.handle.net/10541/69714-
dc.description.abstractThe testis performs two basic functions, sperm production and testosterone secretion. Formation of the testis is genetically controlled; expression of the SRY gene directs the embryonic gonads into the pathway leading to the development of testes. By the fourth week of gestation in humans, the primordial germ cells derived from pluripotent cells of the embryonic epiblast proliferate and migrate from the endoderm of the yolk sac into the undifferentiated gonad, which becomes morphologically distinct during the seventh week of gestation in humans. Histological development of the testis is largely completed by the end of the third month of gestation. Pediatr Blood Cancer (c) 2009 Wiley-Liss, Inc.en
dc.languageENG-
dc.language.isoenen
dc.subjectLeydigen
dc.subjectSertolien
dc.subjectSpermatogenesisen
dc.subjectTesticular Functionen
dc.titleNormal testicular function and spermatogenesis.en
dc.typeArticleen
dc.contributor.departmentDepartment of Endocrinology, Christie Hospital, Manchester, England, UK.en
dc.identifier.journalPediatric Blood & Canceren
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