Testicular seminoma with mediastinal lymphadenopathy -- a diagnostic pitfall.

2.50
Hdl Handle:
http://hdl.handle.net/10541/69560
Title:
Testicular seminoma with mediastinal lymphadenopathy -- a diagnostic pitfall.
Authors:
Jegannathen, Apurna; Taylor, Malcolm B; Jones, M; Logue, John P
Abstract:
Relapse following adjuvant paraaortic radiation therapy in patients with Stage I seminoma is rare, occurring in approximately 4% of men. The majority of relapses are sited in the pelvis but relapse in the mediastinum is also recognised. As such, radiological imaging using chest radiographs remains commonplace in follow-up. However, there are reports of the association of testicular cancers with sarcoidosis and sarcoid-like processes in the mediastinum, emphasising the importance of making histological diagnosis prior to commencement of any treatment. We report on two men treated for testicular seminoma who on follow-up developed mediastinal lymphadenopathy, which was initially assumed to be metastatic seminoma. Both patients underwent mediastinascopy and biopsy prior to commencement of anti-cancer therapy. In both cases, the biopsies showed sarcoidosis, and unnecessary anti-cancer treatment was avoided.
Affiliation:
Departments of Clinical Oncology, Christie Hospital NHS Foundation Trust, Manchester, UK.
Citation:
Testicular seminoma with mediastinal lymphadenopathy -- a diagnostic pitfall. 2009, 82 (977):e85-6 Br J Radiol
Journal:
The British Journal of Radiology
Issue Date:
May-2009
URI:
http://hdl.handle.net/10541/69560
DOI:
10.1259/bjr/40671180
PubMed ID:
19386953
Type:
Article
Language:
en
ISSN:
1748-880X
Appears in Collections:
All Christie Publications ; Radiology; Clinical Oncology

Full metadata record

DC FieldValue Language
dc.contributor.authorJegannathen, Apurna-
dc.contributor.authorTaylor, Malcolm B-
dc.contributor.authorJones, M-
dc.contributor.authorLogue, John P-
dc.date.accessioned2009-06-02T14:12:10Z-
dc.date.available2009-06-02T14:12:10Z-
dc.date.issued2009-05-
dc.identifier.citationTesticular seminoma with mediastinal lymphadenopathy -- a diagnostic pitfall. 2009, 82 (977):e85-6 Br J Radiolen
dc.identifier.issn1748-880X-
dc.identifier.pmid19386953-
dc.identifier.doi10.1259/bjr/40671180-
dc.identifier.urihttp://hdl.handle.net/10541/69560-
dc.description.abstractRelapse following adjuvant paraaortic radiation therapy in patients with Stage I seminoma is rare, occurring in approximately 4% of men. The majority of relapses are sited in the pelvis but relapse in the mediastinum is also recognised. As such, radiological imaging using chest radiographs remains commonplace in follow-up. However, there are reports of the association of testicular cancers with sarcoidosis and sarcoid-like processes in the mediastinum, emphasising the importance of making histological diagnosis prior to commencement of any treatment. We report on two men treated for testicular seminoma who on follow-up developed mediastinal lymphadenopathy, which was initially assumed to be metastatic seminoma. Both patients underwent mediastinascopy and biopsy prior to commencement of anti-cancer therapy. In both cases, the biopsies showed sarcoidosis, and unnecessary anti-cancer treatment was avoided.en
dc.language.isoenen
dc.subjectTesticular Canceren
dc.subject.meshAdult-
dc.subject.meshBiopsy-
dc.subject.meshDiagnosis, Differential-
dc.subject.meshHumans-
dc.subject.meshLymphatic Diseases-
dc.subject.meshMale-
dc.subject.meshMediastinal Diseases-
dc.subject.meshMediastinoscopy-
dc.subject.meshMediastinum-
dc.subject.meshSarcoidosis-
dc.subject.meshSeminoma-
dc.subject.meshTesticular Neoplasms-
dc.subject.meshTomography, X-Ray Computed-
dc.titleTesticular seminoma with mediastinal lymphadenopathy -- a diagnostic pitfall.en
dc.typeArticleen
dc.contributor.departmentDepartments of Clinical Oncology, Christie Hospital NHS Foundation Trust, Manchester, UK.en
dc.identifier.journalThe British Journal of Radiologyen

Related articles on PubMed

All Items in Christie are protected by copyright, with all rights reserved, unless otherwise indicated.