The impact of radiotherapy on swallowing and speech in patients who undergo total laryngectomy.

2.50
Hdl Handle:
http://hdl.handle.net/10541/67986
Title:
The impact of radiotherapy on swallowing and speech in patients who undergo total laryngectomy.
Authors:
De Casso, Carmen; Slevin, Nicholas J ( 0000-0002-3367-7013 ) ; Homer, Jarrod J
Abstract:
OBJECTIVES: Quality of life studies have shown no detrimental effect with radiotherapy (RT) in patients who have a total laryngectomy. We wished to determine the effect of RT (initial or postoperative) specifically on the swallowing and voice function in patients treated by total laryngectomy (TL) for carcinoma of the larynx. DESIGN: Multicenter chart review. SETTING: Multicenter study in the Greater Manchester and Lancashire area. PARTICIPANTS: A total of 121 postlaryngectomy patients all of whom had completed definitive treatment at least 6 months before this study. Twenty-six patients had total laryngectomy as a single modality treatment and 95 had total laryngectomy and radiotherapy. MAIN OUTCOME MEASURES: Swallowing (solid food, soft diet or fluid/PEG) and voice development. RESULTS: Swallowing was better in the group who had no radiotherapy (P = 0.0037). There was no difference in voice function between the two groups. We also demonstrated that females had a worse swallowing outcome (P = 0.0101), as did advanced nodal stage (P = 0.001). CONCLUSIONS: RT adversely affects the swallowing results but not the speech results after TL when given either as initial treatment or postoperatively. This should be kept in mind in the decision-making process in the treatment of patients with carcinoma of the larynx.
Affiliation:
University Department of Otolaryngology-Head and Neck Surgery, Manchester Royal Infirmary, Manchester, UK. cdecasso@doctors.org.uk
Citation:
The impact of radiotherapy on swallowing and speech in patients who undergo total laryngectomy. 2008, 139 (6):792- 797 Otolaryngol Head Neck Surg
Journal:
Otolaryngology--Head and Neck Surgery
Issue Date:
Dec-2008
URI:
http://hdl.handle.net/10541/67986
DOI:
10.1016/j.otohns.2008.08.023
PubMed ID:
19041505
Type:
Article
Language:
en
ISSN:
0194-5998
Appears in Collections:
All Christie Publications ; Clinical Oncology; Surgery

Full metadata record

DC FieldValue Language
dc.contributor.authorDe Casso, Carmen-
dc.contributor.authorSlevin, Nicholas J-
dc.contributor.authorHomer, Jarrod J-
dc.date.accessioned2009-05-12T18:08:00Z-
dc.date.available2009-05-12T18:08:00Z-
dc.date.issued2008-12-
dc.identifier.citationThe impact of radiotherapy on swallowing and speech in patients who undergo total laryngectomy. 2008, 139 (6):792- 797 Otolaryngol Head Neck Surgen
dc.identifier.issn0194-5998-
dc.identifier.pmid19041505-
dc.identifier.doi10.1016/j.otohns.2008.08.023-
dc.identifier.urihttp://hdl.handle.net/10541/67986-
dc.description.abstractOBJECTIVES: Quality of life studies have shown no detrimental effect with radiotherapy (RT) in patients who have a total laryngectomy. We wished to determine the effect of RT (initial or postoperative) specifically on the swallowing and voice function in patients treated by total laryngectomy (TL) for carcinoma of the larynx. DESIGN: Multicenter chart review. SETTING: Multicenter study in the Greater Manchester and Lancashire area. PARTICIPANTS: A total of 121 postlaryngectomy patients all of whom had completed definitive treatment at least 6 months before this study. Twenty-six patients had total laryngectomy as a single modality treatment and 95 had total laryngectomy and radiotherapy. MAIN OUTCOME MEASURES: Swallowing (solid food, soft diet or fluid/PEG) and voice development. RESULTS: Swallowing was better in the group who had no radiotherapy (P = 0.0037). There was no difference in voice function between the two groups. We also demonstrated that females had a worse swallowing outcome (P = 0.0101), as did advanced nodal stage (P = 0.001). CONCLUSIONS: RT adversely affects the swallowing results but not the speech results after TL when given either as initial treatment or postoperatively. This should be kept in mind in the decision-making process in the treatment of patients with carcinoma of the larynx.en
dc.language.isoenen
dc.subjectLaryngeal Canceren
dc.subject.meshAge Factors-
dc.subject.meshAged-
dc.subject.meshCarcinoma, Squamous Cell-
dc.subject.meshChi-Square Distribution-
dc.subject.meshCombined Modality Therapy-
dc.subject.meshDeglutition Disorders-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshLaryngeal Neoplasms-
dc.subject.meshLaryngectomy-
dc.subject.meshLogistic Models-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshQuality of Life-
dc.subject.meshRadiotherapy Dosage-
dc.subject.meshSex Factors-
dc.subject.meshTreatment Outcome-
dc.subject.meshVoice Disorders-
dc.titleThe impact of radiotherapy on swallowing and speech in patients who undergo total laryngectomy.en
dc.typeArticleen
dc.contributor.departmentUniversity Department of Otolaryngology-Head and Neck Surgery, Manchester Royal Infirmary, Manchester, UK. cdecasso@doctors.org.uken
dc.identifier.journalOtolaryngology--Head and Neck Surgeryen

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