New insights into the mechanisms of action of radioimmunotherapy in lymphoma.

2.50
Hdl Handle:
http://hdl.handle.net/10541/67948
Title:
New insights into the mechanisms of action of radioimmunotherapy in lymphoma.
Authors:
Ivanov, Andrei; Swann, Ruth; Illidge, Timothy M ( 0000-0003-3191-7324 )
Abstract:
The exquisite sensitivity of haematological malignancies to targeted radiation alongside the impressive results achieved by the pioneers in this field suggests that radioimmunotherapy is likely to be a productive area for future clinical research. Recent experimental work has demonstrated that the combination of targeted radiation and antibody effector mechanisms are critical to long-term clearance of tumour. This review provides the background of clinical and biological insights into the mechanisms of action of radioimmunotherapy.
Affiliation:
School of Cancer and Imaging Sciences, Paterson Institute for Cancer Research, University of Manchester, Manchester, UK.
Citation:
New insights into the mechanisms of action of radioimmunotherapy in lymphoma. 2008, 60 (8):987-98 J. Pharm. Pharmacol.
Journal:
The Journal of Pharmacy and Pharmacology
Issue Date:
Aug-2008
URI:
http://hdl.handle.net/10541/67948
DOI:
10.1211/jpp.60.8.0006
PubMed ID:
18644192
Type:
Article
Language:
en
ISSN:
0022-3573
Appears in Collections:
All Paterson Institute for Cancer Research; School of Cancer and Imaging Sciences

Full metadata record

DC FieldValue Language
dc.contributor.authorIvanov, Andrei-
dc.contributor.authorSwann, Ruth-
dc.contributor.authorIllidge, Timothy M-
dc.date.accessioned2009-05-12T16:19:39Z-
dc.date.available2009-05-12T16:19:39Z-
dc.date.issued2008-08-
dc.identifier.citationNew insights into the mechanisms of action of radioimmunotherapy in lymphoma. 2008, 60 (8):987-98 J. Pharm. Pharmacol.en
dc.identifier.issn0022-3573-
dc.identifier.pmid18644192-
dc.identifier.doi10.1211/jpp.60.8.0006-
dc.identifier.urihttp://hdl.handle.net/10541/67948-
dc.description.abstractThe exquisite sensitivity of haematological malignancies to targeted radiation alongside the impressive results achieved by the pioneers in this field suggests that radioimmunotherapy is likely to be a productive area for future clinical research. Recent experimental work has demonstrated that the combination of targeted radiation and antibody effector mechanisms are critical to long-term clearance of tumour. This review provides the background of clinical and biological insights into the mechanisms of action of radioimmunotherapy.en
dc.language.isoenen
dc.subject.meshAlgorithms-
dc.subject.meshAnimals-
dc.subject.meshAntibodies, Monoclonal-
dc.subject.meshDecision Trees-
dc.subject.meshDose-Response Relationship, Drug-
dc.subject.meshHumans-
dc.subject.meshLymphoma-
dc.subject.meshRadioimmunotherapy-
dc.subject.meshRadiopharmaceuticals-
dc.subject.meshRadiotherapy Dosage-
dc.subject.meshTreatment Outcome-
dc.titleNew insights into the mechanisms of action of radioimmunotherapy in lymphoma.en
dc.typeArticleen
dc.contributor.departmentSchool of Cancer and Imaging Sciences, Paterson Institute for Cancer Research, University of Manchester, Manchester, UK.en
dc.identifier.journalThe Journal of Pharmacy and Pharmacologyen

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