Computer-based intensity measurement assists pathologists in scoring PTEN immunohistochemistry - clinical associations in NSCLC patients of the ETOP Lungscape cohort.

2.50
Hdl Handle:
http://hdl.handle.net/10541/621307
Title:
Computer-based intensity measurement assists pathologists in scoring PTEN immunohistochemistry - clinical associations in NSCLC patients of the ETOP Lungscape cohort.
Authors:
Rulle, U; Tsourti, Z; Casanova, R; Deml, K; Verbeken, E; Thunnissen, E; Warth, A; Cheney, R; Sejda, A; Speel, E; Madsen, L; Nonaka, Daisuke ( 0000-0003-4027-5116 ) ; Navarro, A; Sansano, I; Marchetti, A; Finn, S; Monkhorst, K; Kerr, K; Haberecker, M; Wu, C; Zygoura, P; Kammler, R; Geiger, T; Gendreau, S; Schulze, K; Vrugt, B; Wild, P; Moch, H; Weder, W; Ciftlik, A; Dafni, U; Peters, S; Bubendorf, L; Stahel, R; Soltermann, A
Abstract:
PTEN loss is frequently observed in NSCLC and associated with both PI3K activation and tumoral immunosuppression. PTEN immunohistochemistry is a valuable read-out, but lacks standardized staining protocol and cut-off value.
Affiliation:
Institute of Pathology and Molecular Pathology, University Hospital Zurich, 8091 Zurich, Switzerland
Citation:
Computer-based intensity measurement assists pathologists in scoring PTEN immunohistochemistry - clinical associations in NSCLC patients of the ETOP Lungscape cohort. 2018, J Thorac Oncol
Journal:
Journal of Thoracic Oncology
Issue Date:
18-Sep-2018
URI:
http://hdl.handle.net/10541/621307
DOI:
10.1016/j.jtho.2018.08.2034
PubMed ID:
30240851
Type:
Article
Language:
en
ISSN:
1556-1380
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorRulle, Uen
dc.contributor.authorTsourti, Zen
dc.contributor.authorCasanova, Ren
dc.contributor.authorDeml, Ken
dc.contributor.authorVerbeken, Een
dc.contributor.authorThunnissen, Een
dc.contributor.authorWarth, Aen
dc.contributor.authorCheney, Ren
dc.contributor.authorSejda, Aen
dc.contributor.authorSpeel, Een
dc.contributor.authorMadsen, Len
dc.contributor.authorNonaka, Daisukeen
dc.contributor.authorNavarro, Aen
dc.contributor.authorSansano, Ien
dc.contributor.authorMarchetti, Aen
dc.contributor.authorFinn, Sen
dc.contributor.authorMonkhorst, Ken
dc.contributor.authorKerr, Ken
dc.contributor.authorHaberecker, Men
dc.contributor.authorWu, Cen
dc.contributor.authorZygoura, Pen
dc.contributor.authorKammler, Ren
dc.contributor.authorGeiger, Ten
dc.contributor.authorGendreau, Sen
dc.contributor.authorSchulze, Ken
dc.contributor.authorVrugt, Ben
dc.contributor.authorWild, Pen
dc.contributor.authorMoch, Hen
dc.contributor.authorWeder, Wen
dc.contributor.authorCiftlik, Aen
dc.contributor.authorDafni, Uen
dc.contributor.authorPeters, Sen
dc.contributor.authorBubendorf, Len
dc.contributor.authorStahel, Ren
dc.contributor.authorSoltermann, Aen
dc.date.accessioned2018-10-26T20:28:31Z-
dc.date.available2018-10-26T20:28:31Z-
dc.date.issued2018-09-18-
dc.identifier.citationComputer-based intensity measurement assists pathologists in scoring PTEN immunohistochemistry - clinical associations in NSCLC patients of the ETOP Lungscape cohort. 2018, J Thorac Oncolen
dc.identifier.issn1556-1380-
dc.identifier.pmid30240851-
dc.identifier.doi10.1016/j.jtho.2018.08.2034-
dc.identifier.urihttp://hdl.handle.net/10541/621307-
dc.description.abstractPTEN loss is frequently observed in NSCLC and associated with both PI3K activation and tumoral immunosuppression. PTEN immunohistochemistry is a valuable read-out, but lacks standardized staining protocol and cut-off value.en
dc.language.isoenen
dc.rightsArchived with thanks to Journal of thoracic oncology : official publication of the International Association for the Study of Lung Canceren
dc.titleComputer-based intensity measurement assists pathologists in scoring PTEN immunohistochemistry - clinical associations in NSCLC patients of the ETOP Lungscape cohort.en
dc.typeArticleen
dc.contributor.departmentInstitute of Pathology and Molecular Pathology, University Hospital Zurich, 8091 Zurich, Switzerlanden
dc.identifier.journalJournal of Thoracic Oncologyen

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