Incidence and regression of actinic keratoses in organ transplant recipients.

2.50
Hdl Handle:
http://hdl.handle.net/10541/620827
Title:
Incidence and regression of actinic keratoses in organ transplant recipients.
Authors:
Jiyad, Z; Marquart, L; O'Rourke, P; Green, Adèle C
Abstract:
Actinic keratoses (AKs) are highly dynamic lesions and AK activity has been shown to be associated with squamous cell carcinoma (SCC). We sought to explore risk factors which may affect the 12-month turnover of AKs in organ transplant recipients (OTRs). The number of incident AKs, regressed AKs and net change in AK counts were calculated. Negative binomial regression and Poisson regression models were used to estimate rate ratios (RR) for these 3 outcomes. Among 150 renal and 89 liver OTRs, those who spent > 50% of a typical weekday in the sun had a lower rate of AK regression than those who spent minimal time in the sun during a typical weekday. Age, parents' country of origin, hair colour, skin cancer history and recent AK treatment were all significantly associated with AK turnover. Clinically, these risk factors may be used to monitor OTRs at increased risk of SCC.
Affiliation:
Cancer and Population Studies Group, QIMR Berghofer Medical Research Institute, Locked Bag 2000 Royal Brisbane Hospital, Brisbane, Queensland 4029, Australia
Citation:
Incidence and regression of actinic keratoses in organ transplant recipients. 2018, 98(1): 77-81 Acta Derm Venereol
Journal:
Acta Dermato-Venereologica
Issue Date:
12-Jan-2018
URI:
http://hdl.handle.net/10541/620827
DOI:
10.2340/00015555-2783
PubMed ID:
28853496
Type:
Article
Language:
en
ISSN:
1651-2057
Appears in Collections:
All Paterson Institute for Cancer Research

Full metadata record

DC FieldValue Language
dc.contributor.authorJiyad, Zen
dc.contributor.authorMarquart, Len
dc.contributor.authorO'Rourke, Pen
dc.contributor.authorGreen, Adèle Cen
dc.date.accessioned2018-03-13T20:32:16Z-
dc.date.available2018-03-13T20:32:16Z-
dc.date.issued2018-01-12-
dc.identifier.citationIncidence and regression of actinic keratoses in organ transplant recipients. 2018, 98(1): 77-81 Acta Derm Venereolen
dc.identifier.issn1651-2057-
dc.identifier.pmid28853496-
dc.identifier.doi10.2340/00015555-2783-
dc.identifier.urihttp://hdl.handle.net/10541/620827-
dc.description.abstractActinic keratoses (AKs) are highly dynamic lesions and AK activity has been shown to be associated with squamous cell carcinoma (SCC). We sought to explore risk factors which may affect the 12-month turnover of AKs in organ transplant recipients (OTRs). The number of incident AKs, regressed AKs and net change in AK counts were calculated. Negative binomial regression and Poisson regression models were used to estimate rate ratios (RR) for these 3 outcomes. Among 150 renal and 89 liver OTRs, those who spent > 50% of a typical weekday in the sun had a lower rate of AK regression than those who spent minimal time in the sun during a typical weekday. Age, parents' country of origin, hair colour, skin cancer history and recent AK treatment were all significantly associated with AK turnover. Clinically, these risk factors may be used to monitor OTRs at increased risk of SCC.en
dc.language.isoenen
dc.rightsArchived with thanks to Acta dermato-venereologicaen
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshFemale-
dc.subject.meshHair Color-
dc.subject.meshHumans-
dc.subject.meshImmunosuppression-
dc.subject.meshIncidence-
dc.subject.meshKeratosis, Actinic-
dc.subject.meshKidney Transplantation-
dc.subject.meshLiver Transplantation-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshPhenotype-
dc.subject.meshRemission, Spontaneous-
dc.subject.meshRisk Factors-
dc.subject.meshSunlight-
dc.subject.meshTime Factors-
dc.titleIncidence and regression of actinic keratoses in organ transplant recipients.en
dc.typeArticleen
dc.contributor.departmentCancer and Population Studies Group, QIMR Berghofer Medical Research Institute, Locked Bag 2000 Royal Brisbane Hospital, Brisbane, Queensland 4029, Australiaen
dc.identifier.journalActa Dermato-Venereologicaen

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