Estimation of renal function -- what is appropriate in cancer patients?

2.50
Hdl Handle:
http://hdl.handle.net/10541/58715
Title:
Estimation of renal function -- what is appropriate in cancer patients?
Authors:
Barraclough, Lisa H; Field, Catherine; Wieringa, Gilbert E; Swindell, Ric; Livsey, Jacqueline E; Davidson, Susan E
Abstract:
AIMS: To compare the accuracy of renal assessment in patients with cancer using radioisotope glomerular filtration rate (GFR), urine collection for creatinine clearance, Cockroft-Gault, Modification of Diet in Renal Disease (MDRD) and Wright formulae. MATERIALS AND METHODS: Measurements of isotope GFR from 367 patients were compared with estimates from the described methods (Cockroft-Gault, MDRD, Wright). An analysis including a further 252 patients with an isotope GFR < or = 50 ml/min was also carried out. RESULTS: The Wright formula was the most accurate form of estimating renal function for the first study group. The formulae were similar in accuracy in the second study group. CONCLUSIONS: The Wright formula is the most accurate form of estimation of renal function in comparison with the isotope GFR for cancer patients. When there is a large proportion of patients with a low isotope GFR (< or = 50 ml/min), the formulae have similar accuracy.
Affiliation:
Department of Clinical Oncology, Christie Hospital, Manchester, UK. lisahelenbone@hotmail.com
Citation:
Estimation of renal function -- what is appropriate in cancer patients? 2008, 20 (10):721-6 Clin Oncol (R Coll Radiol)
Journal:
Clinical Oncology
Issue Date:
Dec-2008
URI:
http://hdl.handle.net/10541/58715
DOI:
10.1016/j.clon.2008.09.004
PubMed ID:
18995170
Type:
Article
Language:
en
ISSN:
0936-6555
Appears in Collections:
All Christie Publications ; Pathology ; Clinical Oncology

Full metadata record

DC FieldValue Language
dc.contributor.authorBarraclough, Lisa H-
dc.contributor.authorField, Catherine-
dc.contributor.authorWieringa, Gilbert E-
dc.contributor.authorSwindell, Ric-
dc.contributor.authorLivsey, Jacqueline E-
dc.contributor.authorDavidson, Susan E-
dc.date.accessioned2009-04-01T23:19:23Z-
dc.date.available2009-04-01T23:19:23Z-
dc.date.issued2008-12-
dc.identifier.citationEstimation of renal function -- what is appropriate in cancer patients? 2008, 20 (10):721-6 Clin Oncol (R Coll Radiol)en
dc.identifier.issn0936-6555-
dc.identifier.pmid18995170-
dc.identifier.doi10.1016/j.clon.2008.09.004-
dc.identifier.urihttp://hdl.handle.net/10541/58715-
dc.description.abstractAIMS: To compare the accuracy of renal assessment in patients with cancer using radioisotope glomerular filtration rate (GFR), urine collection for creatinine clearance, Cockroft-Gault, Modification of Diet in Renal Disease (MDRD) and Wright formulae. MATERIALS AND METHODS: Measurements of isotope GFR from 367 patients were compared with estimates from the described methods (Cockroft-Gault, MDRD, Wright). An analysis including a further 252 patients with an isotope GFR < or = 50 ml/min was also carried out. RESULTS: The Wright formula was the most accurate form of estimating renal function for the first study group. The formulae were similar in accuracy in the second study group. CONCLUSIONS: The Wright formula is the most accurate form of estimation of renal function in comparison with the isotope GFR for cancer patients. When there is a large proportion of patients with a low isotope GFR (< or = 50 ml/min), the formulae have similar accuracy.en
dc.language.isoenen
dc.subjectGFRen
dc.subjectRenal Canceren
dc.subjectRenal Function Assessmenten
dc.subjectCanceren
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshAlgorithms-
dc.subject.meshChlorides-
dc.subject.meshChromium Compounds-
dc.subject.meshChromium Radioisotopes-
dc.subject.meshCreatinine-
dc.subject.meshDiet-
dc.subject.meshFemale-
dc.subject.meshGlomerular Filtration Rate-
dc.subject.meshHumans-
dc.subject.meshKidney-
dc.subject.meshKidney Diseases-
dc.subject.meshKidney Function Tests-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshNeoplasms-
dc.subject.meshROC Curve-
dc.subject.meshRegression Analysis-
dc.subject.meshYoung Adult-
dc.titleEstimation of renal function -- what is appropriate in cancer patients?en
dc.typeArticleen
dc.contributor.departmentDepartment of Clinical Oncology, Christie Hospital, Manchester, UK. lisahelenbone@hotmail.comen
dc.identifier.journalClinical Oncologyen

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