Benign schwannoma in paranasal sinuses: a clinico-pathological study of five cases, emphasising diagnostic difficulties.

2.50
Hdl Handle:
http://hdl.handle.net/10541/58691
Title:
Benign schwannoma in paranasal sinuses: a clinico-pathological study of five cases, emphasising diagnostic difficulties.
Authors:
Sheikh, Hamid Y; Chakravarthy, R P; Slevin, Nicholas J ( 0000-0002-3367-7013 ) ; Sykes, Andrew J; Banerjee, Saumitra S
Abstract:
OBJECTIVES: To highlight the difficulty in making a correct diagnosis of benign schwannoma in the paranasal region, to raise awareness of this rare condition, and to suggest the most appropriate treatment. METHOD: Retrieval of cases retrospectively from archives of the histopathology department of a major UK cancer centre with central review of all cases. RESULTS: Five cases were identified since 1990 and clinical and pathological features are summarised. Median follow up of patients was 8.1 years. Radiological appearances of local bone invasion and histological features of tumour unencapsulation and hypercellularity could give the mistaken impression of malignant disease and lead to unnecessary over-treatment. CONCLUSION: Central pathological review and clinical awareness is required. Although local recurrence can occur, the prognosis is excellent. The treatment of choice is local excision. Radiotherapy can be considered, but in most cases it would incur unnecessary morbidity.
Affiliation:
Department of Clinical Oncology, Christie Hospital NHS Trust, Manchester, UK. hamid.sheikh@christie-tr.nwest.nhs.uk
Citation:
Benign schwannoma in paranasal sinuses: a clinico-pathological study of five cases, emphasising diagnostic difficulties. 2008, 122 (6):598-602 J Laryngol Otol
Journal:
The Journal of Laryngology and Otology
Issue Date:
Jun-2008
URI:
http://hdl.handle.net/10541/58691
DOI:
10.1017/S0022215107000527
PubMed ID:
17705894
Type:
Article
Language:
en
ISSN:
1748-5460
Appears in Collections:
All Christie Publications ; Pathology ; Clinical Oncology

Full metadata record

DC FieldValue Language
dc.contributor.authorSheikh, Hamid Y-
dc.contributor.authorChakravarthy, R P-
dc.contributor.authorSlevin, Nicholas J-
dc.contributor.authorSykes, Andrew J-
dc.contributor.authorBanerjee, Saumitra S-
dc.date.accessioned2009-04-01T23:16:12Z-
dc.date.available2009-04-01T23:16:12Z-
dc.date.issued2008-06-
dc.identifier.citationBenign schwannoma in paranasal sinuses: a clinico-pathological study of five cases, emphasising diagnostic difficulties. 2008, 122 (6):598-602 J Laryngol Otolen
dc.identifier.issn1748-5460-
dc.identifier.pmid17705894-
dc.identifier.doi10.1017/S0022215107000527-
dc.identifier.urihttp://hdl.handle.net/10541/58691-
dc.description.abstractOBJECTIVES: To highlight the difficulty in making a correct diagnosis of benign schwannoma in the paranasal region, to raise awareness of this rare condition, and to suggest the most appropriate treatment. METHOD: Retrieval of cases retrospectively from archives of the histopathology department of a major UK cancer centre with central review of all cases. RESULTS: Five cases were identified since 1990 and clinical and pathological features are summarised. Median follow up of patients was 8.1 years. Radiological appearances of local bone invasion and histological features of tumour unencapsulation and hypercellularity could give the mistaken impression of malignant disease and lead to unnecessary over-treatment. CONCLUSION: Central pathological review and clinical awareness is required. Although local recurrence can occur, the prognosis is excellent. The treatment of choice is local excision. Radiotherapy can be considered, but in most cases it would incur unnecessary morbidity.en
dc.language.isoenen
dc.subjectParanasal Sinus Canceren
dc.subjectSchwannomaen
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshDiagnosis, Differential-
dc.subject.meshEngland-
dc.subject.meshEthmoid Sinus-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshMaxillary Sinus Neoplasms-
dc.subject.meshMiddle Aged-
dc.subject.meshNeurilemmoma-
dc.subject.meshParanasal Sinus Neoplasms-
dc.subject.meshRetrospective Studies-
dc.subject.meshTomography, X-Ray Computed-
dc.titleBenign schwannoma in paranasal sinuses: a clinico-pathological study of five cases, emphasising diagnostic difficulties.en
dc.typeArticleen
dc.contributor.departmentDepartment of Clinical Oncology, Christie Hospital NHS Trust, Manchester, UK. hamid.sheikh@christie-tr.nwest.nhs.uken
dc.identifier.journalThe Journal of Laryngology and Otologyen

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