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The Manchester Institute Cancer Research UK
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Clinical and Experimental Pharmacology Group29
CEP incorporates teams in pre-clinical drug target validation and biomarker discovery.
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Latest publications
- Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death.9Feb2010
- Detection of BRAF mutations in the tumour and serum of patients enrolled in the AZD6244 (ARRY-142886) advanced melanoma phase II study.8Feb2010
- A small molecule inhibitor of XIAP induces apoptosis and synergises with vinorelbine and cisplatin in NSCLC.9Dec2009
- Contribution of HIF-1 and drug penetrance to oxaliplatin resistance in hypoxic colorectal cancer cells.8Dec2009
- Preclinical efficacy of the bioreductive alkylating agent RH1 against paediatric tumours.8Dec2009