PLK1 and YY1 interaction in follicular lymphoma is associated with unfavourable outcome.

2.50
Hdl Handle:
http://hdl.handle.net/10541/302255
Title:
PLK1 and YY1 interaction in follicular lymphoma is associated with unfavourable outcome.
Authors:
Sandison, H; Usher, S; Karimiani, E; Ashton, Garry; Menasce, Lia P; Radford, John A ( 0000-0001-7898-2786 ) ; Linton, Kim M ( 0000-0002-3294-1548 ) ; Byers, R
Abstract:
Ying Yang 1 (YY1) is a transcription factor involved in both proliferation and apoptosis. It is prognostic in follicular lymphoma (FL), increased protein levels being associated with favourable outcome. PLK1 is a critical regulator of mitosis, playing a role in spindle formation and in regulation of the G2/M cell cycle checkpoint. PLK1 phosphorylates YY1 at the G2/M checkpoint with activation of YY1 and resultant progression from G2 into mitosis.
Affiliation:
The Medical School, The University of Manchester, , Manchester, Greater Manchester, UK.
Citation:
PLK1 and YY1 interaction in follicular lymphoma is associated with unfavourable outcome. 2013, 66 (9):764-7 J Clin Pathol
Journal:
Journal of Clinical Pathology
Issue Date:
Sep-2013
URI:
http://hdl.handle.net/10541/302255
DOI:
10.1136/jclinpath-2013-201461
PubMed ID:
23757039
Type:
Article
Language:
en
ISSN:
1472-4146
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorSandison, Hen_GB
dc.contributor.authorUsher, Sen_GB
dc.contributor.authorKarimiani, Een_GB
dc.contributor.authorAshton, Garryen_GB
dc.contributor.authorMenasce, Lia Pen_GB
dc.contributor.authorRadford, John Aen_GB
dc.contributor.authorLinton, Kim Men_GB
dc.contributor.authorByers, Ren_GB
dc.date.accessioned2013-09-25T11:45:19Z-
dc.date.available2013-09-25T11:45:19Z-
dc.date.issued2013-09-
dc.identifier.citationPLK1 and YY1 interaction in follicular lymphoma is associated with unfavourable outcome. 2013, 66 (9):764-7 J Clin Patholen_GB
dc.identifier.issn1472-4146-
dc.identifier.pmid23757039-
dc.identifier.doi10.1136/jclinpath-2013-201461-
dc.identifier.urihttp://hdl.handle.net/10541/302255-
dc.description.abstractYing Yang 1 (YY1) is a transcription factor involved in both proliferation and apoptosis. It is prognostic in follicular lymphoma (FL), increased protein levels being associated with favourable outcome. PLK1 is a critical regulator of mitosis, playing a role in spindle formation and in regulation of the G2/M cell cycle checkpoint. PLK1 phosphorylates YY1 at the G2/M checkpoint with activation of YY1 and resultant progression from G2 into mitosis.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to Journal of clinical pathologyen_GB
dc.titlePLK1 and YY1 interaction in follicular lymphoma is associated with unfavourable outcome.en
dc.typeArticleen
dc.contributor.departmentThe Medical School, The University of Manchester, , Manchester, Greater Manchester, UK.en_GB
dc.identifier.journalJournal of Clinical Pathologyen_GB

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