YY1 expression predicts favourable outcome in follicular lymphoma.

4.00
Hdl Handle:
http://hdl.handle.net/10541/201091
Title:
YY1 expression predicts favourable outcome in follicular lymphoma.
Authors:
Naidoo, Khimara; Clay, V; Hoyland, J A; Swindell, Ric; Linton, Kim M ( 0000-0002-3294-1548 ) ; Illidge, Timothy M ( 0000-0003-3191-7324 ) ; Radford, John A ( 0000-0001-7898-2786 ) ; Byers, RJ
Abstract:
Follicular lymphoma is the second most common type of non-Hodgkin's lymphoma worldwide. The majority of patients diagnosed as having follicular lymphoma have an indolent form of the disease, but a subset of patients have aggressive disease with a shorter survival interval. Optimal treatment stratification requires a distinction between these two groups, though there are presently few prognostic biomarkers available. The transcription factor YY1 has been shown to play an important role in cancer biology. The authors have previously reported a correlation of Yin Yang 1 (YY1) mRNA levels with survival in FL. This study aimed to validate these findings at the protein level.
Affiliation:
School of Cancer and Enabling Sciences, Faculty of Medical and Human Sciences, The University of Manchester, Manchester, UK.
Citation:
YY1 expression predicts favourable outcome in follicular lymphoma. 2011, 64 (2):125-9 J. Clin. Pathol.
Journal:
Journal of Clinical Pathology
Issue Date:
Feb-2011
URI:
http://hdl.handle.net/10541/201091
DOI:
10.1136/jcp.2010.078188
PubMed ID:
21109702
Type:
Article
Language:
en
ISSN:
1472-4146
Appears in Collections:
All Christie Publications ; Medical Oncology

Full metadata record

DC FieldValue Language
dc.contributor.authorNaidoo, Khimaraen
dc.contributor.authorClay, Ven
dc.contributor.authorHoyland, J Aen
dc.contributor.authorSwindell, Ricen
dc.contributor.authorLinton, Kim Men
dc.contributor.authorIllidge, Timothy Men
dc.contributor.authorRadford, John Aen
dc.contributor.authorByers, RJen
dc.date.accessioned2012-01-09T22:43:58Z-
dc.date.available2012-01-09T22:43:58Z-
dc.date.issued2011-02-
dc.identifier.citationYY1 expression predicts favourable outcome in follicular lymphoma. 2011, 64 (2):125-9 J. Clin. Pathol.en
dc.identifier.issn1472-4146-
dc.identifier.pmid21109702-
dc.identifier.doi10.1136/jcp.2010.078188-
dc.identifier.urihttp://hdl.handle.net/10541/201091-
dc.description.abstractFollicular lymphoma is the second most common type of non-Hodgkin's lymphoma worldwide. The majority of patients diagnosed as having follicular lymphoma have an indolent form of the disease, but a subset of patients have aggressive disease with a shorter survival interval. Optimal treatment stratification requires a distinction between these two groups, though there are presently few prognostic biomarkers available. The transcription factor YY1 has been shown to play an important role in cancer biology. The authors have previously reported a correlation of Yin Yang 1 (YY1) mRNA levels with survival in FL. This study aimed to validate these findings at the protein level.en
dc.language.isoenen
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshFemale-
dc.subject.meshFollow-Up Studies-
dc.subject.meshHumans-
dc.subject.meshKaplan-Meier Estimate-
dc.subject.meshKi-67 Antigen-
dc.subject.meshLymphoma, Follicular-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshNeoplasm Proteins-
dc.subject.meshPrognosis-
dc.subject.meshTumor Markers, Biological-
dc.subject.meshYY1 Transcription Factor-
dc.titleYY1 expression predicts favourable outcome in follicular lymphoma.en
dc.typeArticleen
dc.contributor.departmentSchool of Cancer and Enabling Sciences, Faculty of Medical and Human Sciences, The University of Manchester, Manchester, UK.en
dc.identifier.journalJournal of Clinical Pathologyen

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