Decreased vagal power during treadmill walking in patients with chronic fatigue syndrome.

2.50
Hdl Handle:
http://hdl.handle.net/10541/109861
Title:
Decreased vagal power during treadmill walking in patients with chronic fatigue syndrome.
Authors:
Cordero, D L; Sisto, S A; Tapp, W N; LaManca, Jaddy J; Pareja, J G; Natelson, B H
Abstract:
The purpose of this study was to determine if patients with the chronic fatigue syndrome have less vagal power during walking and rest periods following walking, in comparison to a group of healthy controls. Eleven patients (ten women and one man) who fulfilled the case definition for chronic fatigue syndrome modified to reduce heterogeneity and eleven healthy, but sedentary, age- and sex-matched controls walked on a treadmill at 2.5 mph four times each for 4 min duration. Between each period of walking, subjects were given a 4-min seated rest period. Vagal power, a Fourier-based measure of cardiac, parasympathetic activity in the frequency range of 0.15 to 1.0 Hz, was computed. In each period of walking and in one period of rest, patients had significantly less vagal power than the control subjects despite there being no significant group-wise differences in mean heart rate, tidal volume, minute volume, respiratory rate, oxygen consumption or total spectrum power. Further, patients had a significant decline in resting vagal power after periods of walking. These results suggest a subtle abnormality in vagal activity to the heart in patients with the chronic fatigue syndrome and may explain, in part, their post-exertional symptom exacerbation.
Affiliation:
Fatigue Research Center, DVA Medical Center, East Orange, NJ 07018, USA.
Citation:
Decreased vagal power during treadmill walking in patients with chronic fatigue syndrome. 1996, 6 (6):329-33 Clin. Auton. Res.
Journal:
Clinical Autonomic Research
Issue Date:
Dec-1996
URI:
http://hdl.handle.net/10541/109861
DOI:
10.1007/BF02556303
PubMed ID:
8985621
Type:
Article
Language:
en
ISSN:
0959-9851
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorCordero, D Len
dc.contributor.authorSisto, S Aen
dc.contributor.authorTapp, W Nen
dc.contributor.authorLaManca, Jaddy Jen
dc.contributor.authorPareja, J Gen
dc.contributor.authorNatelson, B Hen
dc.date.accessioned2010-08-18T15:45:00Z-
dc.date.available2010-08-18T15:45:00Z-
dc.date.issued1996-12-
dc.identifier.citationDecreased vagal power during treadmill walking in patients with chronic fatigue syndrome. 1996, 6 (6):329-33 Clin. Auton. Res.en
dc.identifier.issn0959-9851-
dc.identifier.pmid8985621-
dc.identifier.doi10.1007/BF02556303-
dc.identifier.urihttp://hdl.handle.net/10541/109861-
dc.description.abstractThe purpose of this study was to determine if patients with the chronic fatigue syndrome have less vagal power during walking and rest periods following walking, in comparison to a group of healthy controls. Eleven patients (ten women and one man) who fulfilled the case definition for chronic fatigue syndrome modified to reduce heterogeneity and eleven healthy, but sedentary, age- and sex-matched controls walked on a treadmill at 2.5 mph four times each for 4 min duration. Between each period of walking, subjects were given a 4-min seated rest period. Vagal power, a Fourier-based measure of cardiac, parasympathetic activity in the frequency range of 0.15 to 1.0 Hz, was computed. In each period of walking and in one period of rest, patients had significantly less vagal power than the control subjects despite there being no significant group-wise differences in mean heart rate, tidal volume, minute volume, respiratory rate, oxygen consumption or total spectrum power. Further, patients had a significant decline in resting vagal power after periods of walking. These results suggest a subtle abnormality in vagal activity to the heart in patients with the chronic fatigue syndrome and may explain, in part, their post-exertional symptom exacerbation.en
dc.language.isoenen
dc.subject.meshAnalysis of Variance-
dc.subject.meshCase-Control Studies-
dc.subject.meshElectrocardiography-
dc.subject.meshExercise Test-
dc.subject.meshFatigue Syndrome, Chronic-
dc.subject.meshFemale-
dc.subject.meshHeart Rate-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshVagus Nerve-
dc.subject.meshWalking-
dc.titleDecreased vagal power during treadmill walking in patients with chronic fatigue syndrome.en
dc.typeArticleen
dc.contributor.departmentFatigue Research Center, DVA Medical Center, East Orange, NJ 07018, USA.en
dc.identifier.journalClinical Autonomic Researchen
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