Primary malignant lymphoma of the thyroid: a clinicopathological analysis.

2.50
Hdl Handle:
http://hdl.handle.net/10541/109618
Title:
Primary malignant lymphoma of the thyroid: a clinicopathological analysis.
Authors:
Logue, John P; Hale, R J; Stewart, Alan L; Duthie, M B; Banerjee, Saumitra S
Abstract:
A retrospective analysis of 70 patients with primary malignant lymphoma of the thyroid treated at this institute between 1965-1983 has been conducted. The clinicopathological features and prognostic factors have been studied. The mean age was 67.5 years and there was a marked female:male ratio of 8:1. A total of 32 (45.7%) Stage IE and 38 (54.3%) Stage IIE patients were identified. In 64 cases histological material was reviewed and classified employing the Kiel classification. All the tumors were of B cell lineage and the majority were follicle center cell type. A biopsy only was performed in 27 patients, lobectomy in 11 patients, subtotal thyroidectomy in 27 and macroscopic thyroidectomy in 5 patients. All patients were treated with radiotherapy. The overall 5-year survival was 42%, with 63% for Stage IE and 27% for Stage IIE. The corrected overall 5-year survival was 49% with 68% for Stage IE and 36% for Stage IIE. The corresponding overall relapse free survival was 42% with 60% for Stage IE, and 31% for Stage IIE. Factors of prognostic significance for relapse and survival were stage, radiotherapy dose, stridor, retrosternal extension and fixation.
Affiliation:
Department of Radiotherapy and Oncology, Christie Hospital and Holt Radium Institute, Manchester, U.K.
Citation:
Primary malignant lymphoma of the thyroid: a clinicopathological analysis. 1992, 22 (5):929-33 Int J Radiat Oncol Biol Phys
Journal:
International Journal of Radiation Oncology, Biology, Physics
Issue Date:
1992
URI:
http://hdl.handle.net/10541/109618
PubMed ID:
1555984
Type:
Article
Language:
en
ISSN:
0360-3016
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorLogue, John Pen
dc.contributor.authorHale, R Jen
dc.contributor.authorStewart, Alan Len
dc.contributor.authorDuthie, M Ben
dc.contributor.authorBanerjee, Saumitra Sen
dc.date.accessioned2010-08-16T13:20:39Z-
dc.date.available2010-08-16T13:20:39Z-
dc.date.issued1992-
dc.identifier.citationPrimary malignant lymphoma of the thyroid: a clinicopathological analysis. 1992, 22 (5):929-33 Int J Radiat Oncol Biol Physen
dc.identifier.issn0360-3016-
dc.identifier.pmid1555984-
dc.identifier.urihttp://hdl.handle.net/10541/109618-
dc.description.abstractA retrospective analysis of 70 patients with primary malignant lymphoma of the thyroid treated at this institute between 1965-1983 has been conducted. The clinicopathological features and prognostic factors have been studied. The mean age was 67.5 years and there was a marked female:male ratio of 8:1. A total of 32 (45.7%) Stage IE and 38 (54.3%) Stage IIE patients were identified. In 64 cases histological material was reviewed and classified employing the Kiel classification. All the tumors were of B cell lineage and the majority were follicle center cell type. A biopsy only was performed in 27 patients, lobectomy in 11 patients, subtotal thyroidectomy in 27 and macroscopic thyroidectomy in 5 patients. All patients were treated with radiotherapy. The overall 5-year survival was 42%, with 63% for Stage IE and 27% for Stage IIE. The corrected overall 5-year survival was 49% with 68% for Stage IE and 36% for Stage IIE. The corresponding overall relapse free survival was 42% with 60% for Stage IE, and 31% for Stage IIE. Factors of prognostic significance for relapse and survival were stage, radiotherapy dose, stridor, retrosternal extension and fixation.en
dc.language.isoenen
dc.subjectThyroid Canceren
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshCombined Modality Therapy-
dc.subject.meshEngland-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshLymphoma, B-Cell-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshPrognosis-
dc.subject.meshRetrospective Studies-
dc.subject.meshSurvival Rate-
dc.subject.meshThyroid Neoplasms-
dc.titlePrimary malignant lymphoma of the thyroid: a clinicopathological analysis.en
dc.typeArticleen
dc.contributor.departmentDepartment of Radiotherapy and Oncology, Christie Hospital and Holt Radium Institute, Manchester, U.K.en
dc.identifier.journalInternational Journal of Radiation Oncology, Biology, Physicsen

Related articles on PubMed

All Items in Christie are protected by copyright, with all rights reserved, unless otherwise indicated.