Flow cytometric DNA characteristics of radiation colitis--a preliminary study.

2.50
Hdl Handle:
http://hdl.handle.net/10541/109520
Title:
Flow cytometric DNA characteristics of radiation colitis--a preliminary study.
Authors:
Pearson, J M; Kumar, Shant; Butterworth, D M; Schofield, Philip F; Haboubi, Najib
Abstract:
The DNA status of 12 rectal biopsies, taken during the investigation of radiation proctitis, was investigated. Of these six were in the acute phase and six in the chronic phase. All of the acute biopsies had diploid DNA, despite bizarre histological epithelial cell appearances. Two of the chronic phase biopsies were to have aneuploid DNA profiles. This finding may be relevant to the increased risk of malignancy in irradiated tissues.
Affiliation:
Department of Histopathology, University Hospital of South Manchester, West Didsbury, England.
Citation:
Flow cytometric DNA characteristics of radiation colitis--a preliminary study., 12 (5):1647-9 Anticancer Res
Journal:
Anticancer Research
Issue Date:
1992
URI:
http://hdl.handle.net/10541/109520
PubMed ID:
1444231
Type:
Article
Language:
en
ISSN:
0250-7005
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorPearson, J Men
dc.contributor.authorKumar, Shanten
dc.contributor.authorButterworth, D Men
dc.contributor.authorSchofield, Philip Fen
dc.contributor.authorHaboubi, Najiben
dc.date.accessioned2010-08-11T17:34:44Z-
dc.date.available2010-08-11T17:34:44Z-
dc.date.issued1992-
dc.identifier.citationFlow cytometric DNA characteristics of radiation colitis--a preliminary study., 12 (5):1647-9 Anticancer Resen
dc.identifier.issn0250-7005-
dc.identifier.pmid1444231-
dc.identifier.urihttp://hdl.handle.net/10541/109520-
dc.description.abstractThe DNA status of 12 rectal biopsies, taken during the investigation of radiation proctitis, was investigated. Of these six were in the acute phase and six in the chronic phase. All of the acute biopsies had diploid DNA, despite bizarre histological epithelial cell appearances. Two of the chronic phase biopsies were to have aneuploid DNA profiles. This finding may be relevant to the increased risk of malignancy in irradiated tissues.en
dc.language.isoenen
dc.subject.meshAcute Disease-
dc.subject.meshBiopsy-
dc.subject.meshCell Cycle-
dc.subject.meshChronic Disease-
dc.subject.meshColitis-
dc.subject.meshDNA-
dc.subject.meshFlow Cytometry-
dc.subject.meshHumans-
dc.subject.meshPloidies-
dc.subject.meshRadiation Injuries-
dc.subject.meshRadiotherapy-
dc.titleFlow cytometric DNA characteristics of radiation colitis--a preliminary study.en
dc.typeArticleen
dc.contributor.departmentDepartment of Histopathology, University Hospital of South Manchester, West Didsbury, England.en
dc.identifier.journalAnticancer Researchen

Related articles on PubMed

All Items in Christie are protected by copyright, with all rights reserved, unless otherwise indicated.