An analysis of breast motion using high-frequency, dense surface points captured by an optical sensor during radiotherapy treatment delivery.

2.50
Hdl Handle:
http://hdl.handle.net/10541/109239
Title:
An analysis of breast motion using high-frequency, dense surface points captured by an optical sensor during radiotherapy treatment delivery.
Authors:
Price, Gareth J; Sharrock, Phillip J; Marchant, Thomas E; Parkhurst, J M; Burton, D; Jain, Pooja; Price, Patricia M; Moore, Christopher J
Abstract:
Patient motion is an important factor affecting the quality of external beam radiotherapy in breast patients. We analyse the motion of a dense set of surface points on breast patients throughout their treatment schedule to assess the magnitude and stability of motion, in particular, with respect to breast volume. We use an optical sensor to measure the surface motion of 13 breast cancer patients. Patients were divided into two cohorts dependent upon breast volume. Measurements were made during radiotherapy treatment beam delivery for an average of 12 fractions per patient (total 158 datasets). The motion of each surface point is parameterized in terms of its period, amplitude and relative phase. Inter-comparison of the motion parameters across treatment schedules and between patients is made through the creation of corresponding regions on the breast surfaces. The motion period is spatially uniform and is similar in both patient groups (mean 4 s), with the small volume cohort exhibiting greater inter-fraction period variability. The mean motion amplitude is also similar in both groups with a range between 2 mm and 4 mm and an inter-fraction variability generally less than 1 mm. There is a phase lag of up to 0.4 s across the breast, led by the sternum. Breast patient motion is reasonably stable between and during treatment fractions, with the large volume cohort exhibiting greater repeatability than the small volume one.
Affiliation:
North Western Medical Physics, The Christie NHS Foundation Trust, Manchester, UK. Gareth.Price@physics.cr.man.ac.uk
Citation:
An analysis of breast motion using high-frequency, dense surface points captured by an optical sensor during radiotherapy treatment delivery. 2009, 54 (21):6515-33 Phys Med Biol
Journal:
Physics in Medicine and Biology
Issue Date:
7-Nov-2009
URI:
http://hdl.handle.net/10541/109239
DOI:
10.1088/0031-9155/54/21/005
PubMed ID:
19826200
Type:
Article
Language:
en
ISSN:
1361-6560
Appears in Collections:
All Christie Publications ; Christie Medical Physics and Engineering Research; Academic Department of Radiation Oncology - ADRO

Full metadata record

DC FieldValue Language
dc.contributor.authorPrice, Gareth Jen
dc.contributor.authorSharrock, Phillip Jen
dc.contributor.authorMarchant, Thomas Een
dc.contributor.authorParkhurst, J Men
dc.contributor.authorBurton, Den
dc.contributor.authorJain, Poojaen
dc.contributor.authorPrice, Patricia Men
dc.contributor.authorMoore, Christopher Jen
dc.date.accessioned2010-08-07T10:52:47Z-
dc.date.available2010-08-07T10:52:47Z-
dc.date.issued2009-11-07-
dc.identifier.citationAn analysis of breast motion using high-frequency, dense surface points captured by an optical sensor during radiotherapy treatment delivery. 2009, 54 (21):6515-33 Phys Med Biolen
dc.identifier.issn1361-6560-
dc.identifier.pmid19826200-
dc.identifier.doi10.1088/0031-9155/54/21/005-
dc.identifier.urihttp://hdl.handle.net/10541/109239-
dc.description.abstractPatient motion is an important factor affecting the quality of external beam radiotherapy in breast patients. We analyse the motion of a dense set of surface points on breast patients throughout their treatment schedule to assess the magnitude and stability of motion, in particular, with respect to breast volume. We use an optical sensor to measure the surface motion of 13 breast cancer patients. Patients were divided into two cohorts dependent upon breast volume. Measurements were made during radiotherapy treatment beam delivery for an average of 12 fractions per patient (total 158 datasets). The motion of each surface point is parameterized in terms of its period, amplitude and relative phase. Inter-comparison of the motion parameters across treatment schedules and between patients is made through the creation of corresponding regions on the breast surfaces. The motion period is spatially uniform and is similar in both patient groups (mean 4 s), with the small volume cohort exhibiting greater inter-fraction period variability. The mean motion amplitude is also similar in both groups with a range between 2 mm and 4 mm and an inter-fraction variability generally less than 1 mm. There is a phase lag of up to 0.4 s across the breast, led by the sternum. Breast patient motion is reasonably stable between and during treatment fractions, with the large volume cohort exhibiting greater repeatability than the small volume one.en
dc.language.isoenen
dc.subjectBreast Canceren
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshBreast-
dc.subject.meshBreast Neoplasms-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshMiddle Aged-
dc.subject.meshModels, Statistical-
dc.subject.meshMotion-
dc.subject.meshMovement-
dc.subject.meshOptics and Photonics-
dc.subject.meshRadiotherapy Dosage-
dc.subject.meshRadiotherapy Planning, Computer-Assisted-
dc.subject.meshRadiotherapy, Intensity-Modulated-
dc.titleAn analysis of breast motion using high-frequency, dense surface points captured by an optical sensor during radiotherapy treatment delivery.en
dc.typeArticleen
dc.contributor.departmentNorth Western Medical Physics, The Christie NHS Foundation Trust, Manchester, UK. Gareth.Price@physics.cr.man.ac.uken
dc.identifier.journalPhysics in Medicine and Biologyen

Related articles on PubMed

All Items in Christie are protected by copyright, with all rights reserved, unless otherwise indicated.