Cancer risk in second degree relatives of children with soft tissue sarcoma.

2.50
Hdl Handle:
http://hdl.handle.net/10541/108404
Title:
Cancer risk in second degree relatives of children with soft tissue sarcoma.
Authors:
Hartley, Ann L; Birch, Jillian M; Teare, M Dawn; Blair, Val; Kelsey, Anna M
Abstract:
The risk of cancer in the second degree relatives of a population-based series of children with soft tissue sarcoma was studied in relation to (i) various characteristics in these relatives, (ii) certain clinical features in the index children previously identified as risk factors for cancer in their first degree relatives. Overall there was a non-significant deficit of cancers in the second degree relatives (RR = 0.88) and cancer risk was unrelated to type or site of cancer, type of relative, or to risk factors in the index case. The findings indicate that although the families investigated may include a proportion with the Li-Fraumeni cancer family syndrome, the increased cancer risk already reported in the first degree relatives does not extent to second degree relatives in general.
Affiliation:
Cancer Research Campaign Paediatric and Familial Cancer Research Group, Christie Hospital, Manchester, UK.
Citation:
Cancer risk in second degree relatives of children with soft tissue sarcoma. 1991, 63 (6):959-62 Br. J. Cancer
Journal:
British Journal of Cancer
Issue Date:
Jun-1991
URI:
http://hdl.handle.net/10541/108404
PubMed ID:
2069851
Type:
Article
Language:
en
ISSN:
0007-0920
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorHartley, Ann Len
dc.contributor.authorBirch, Jillian Men
dc.contributor.authorTeare, M Dawnen
dc.contributor.authorBlair, Valen
dc.contributor.authorKelsey, Anna Men
dc.date.accessioned2010-07-27T10:57:42Z-
dc.date.available2010-07-27T10:57:42Z-
dc.date.issued1991-06-
dc.identifier.citationCancer risk in second degree relatives of children with soft tissue sarcoma. 1991, 63 (6):959-62 Br. J. Canceren
dc.identifier.issn0007-0920-
dc.identifier.pmid2069851-
dc.identifier.urihttp://hdl.handle.net/10541/108404-
dc.description.abstractThe risk of cancer in the second degree relatives of a population-based series of children with soft tissue sarcoma was studied in relation to (i) various characteristics in these relatives, (ii) certain clinical features in the index children previously identified as risk factors for cancer in their first degree relatives. Overall there was a non-significant deficit of cancers in the second degree relatives (RR = 0.88) and cancer risk was unrelated to type or site of cancer, type of relative, or to risk factors in the index case. The findings indicate that although the families investigated may include a proportion with the Li-Fraumeni cancer family syndrome, the increased cancer risk already reported in the first degree relatives does not extent to second degree relatives in general.en
dc.language.isoenen
dc.subjectCanceren
dc.subjectSoft Tissue Canceren
dc.subject.meshAdolescent-
dc.subject.meshAge Factors-
dc.subject.meshChild-
dc.subject.meshEngland-
dc.subject.meshFamily-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshNeoplasms-
dc.subject.meshRegistries-
dc.subject.meshRisk Factors-
dc.subject.meshSarcoma-
dc.subject.meshSex Characteristics-
dc.subject.meshSoft Tissue Neoplasms-
dc.titleCancer risk in second degree relatives of children with soft tissue sarcoma.en
dc.typeArticleen
dc.contributor.departmentCancer Research Campaign Paediatric and Familial Cancer Research Group, Christie Hospital, Manchester, UK.en
dc.identifier.journalBritish Journal of Canceren

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