Suitability of cisplatin solutions for 14-day continuous infusion by ambulatory pump.

2.50
Hdl Handle:
http://hdl.handle.net/10541/108141
Title:
Suitability of cisplatin solutions for 14-day continuous infusion by ambulatory pump.
Authors:
Hrubisko, M; McGown, Alan T; Prendiville, Joseph A; Radford, John A ( 0000-0001-7898-2786 ) ; Thatcher, Nick; Fox, Brian W
Abstract:
The stability of cisplatin (DDP) solutions (1 and 1.6 mg/ml in saline-mannitol) in plastic infusion bags was studied for up to 14 days at 25 degrees C, 37 degrees C and 60 degrees C. Small changes in the solution were observed, but no evidence of any decomposition product was seen. Some precipitation of DDP was seen in the 1.6-mg/ml solution at the lower temperatures. Fluid loss from the bags was significant at the higher temperatures.
Affiliation:
Cancer Research Institute, Slovak Academy of Sciences, Bratislava.
Citation:
Suitability of cisplatin solutions for 14-day continuous infusion by ambulatory pump. 1992, 29 (3):252-5 Cancer Chemother Pharmacol
Journal:
Cancer Chemotherapy and Pharmacology
Issue Date:
1992
URI:
http://hdl.handle.net/10541/108141
DOI:
10.1007/BF00686261
PubMed ID:
1733559
Type:
Article
Language:
en
ISSN:
0344-5704
Appears in Collections:
All Christie Publications ; All Paterson Institute for Cancer Research

Full metadata record

DC FieldValue Language
dc.contributor.authorHrubisko, Men
dc.contributor.authorMcGown, Alan Ten
dc.contributor.authorPrendiville, Joseph Aen
dc.contributor.authorRadford, John Aen
dc.contributor.authorThatcher, Nicken
dc.contributor.authorFox, Brian Wen
dc.date.accessioned2010-07-22T09:04:03Z-
dc.date.available2010-07-22T09:04:03Z-
dc.date.issued1992-
dc.identifier.citationSuitability of cisplatin solutions for 14-day continuous infusion by ambulatory pump. 1992, 29 (3):252-5 Cancer Chemother Pharmacolen
dc.identifier.issn0344-5704-
dc.identifier.pmid1733559-
dc.identifier.doi10.1007/BF00686261-
dc.identifier.urihttp://hdl.handle.net/10541/108141-
dc.description.abstractThe stability of cisplatin (DDP) solutions (1 and 1.6 mg/ml in saline-mannitol) in plastic infusion bags was studied for up to 14 days at 25 degrees C, 37 degrees C and 60 degrees C. Small changes in the solution were observed, but no evidence of any decomposition product was seen. Some precipitation of DDP was seen in the 1.6-mg/ml solution at the lower temperatures. Fluid loss from the bags was significant at the higher temperatures.en
dc.language.isoenen
dc.subject.meshChromatography, High Pressure Liquid-
dc.subject.meshCisplatin-
dc.subject.meshDrug Stability-
dc.subject.meshInfusion Pumps-
dc.subject.meshSolutions-
dc.subject.meshTemperature-
dc.subject.meshTime Factors-
dc.titleSuitability of cisplatin solutions for 14-day continuous infusion by ambulatory pump.en
dc.typeArticleen
dc.contributor.departmentCancer Research Institute, Slovak Academy of Sciences, Bratislava.en
dc.identifier.journalCancer Chemotherapy and Pharmacologyen

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