The importance of dose and schedule in chemotherapy for small cell lung cancer.

2.50
Hdl Handle:
http://hdl.handle.net/10541/107469
Title:
The importance of dose and schedule in chemotherapy for small cell lung cancer.
Authors:
Ranson, Malcolm R; Thatcher, Nick
Abstract:
To improve the survival outlook for patients with small cell lung cancer a variety of chemotherapy strategies has been adopted. This review focuses on the evidence for schedule dependency, particularly with regard to etoposide, and reviews the use of alternating chemotherapy protocols and weekly regimens in small cell lung cancer treatment. Recent improvements in supportive care, with the use of haemopoietic growth factors and peripheral blood progenitor cells, have led to renewed interest in the concept of dose intensity. Preliminary results of dose intensification in small cell lung cancer are described and future prospects discussed.
Affiliation:
CRC Department of Medical Oncology, University of Manchester, UK.
Citation:
The importance of dose and schedule in chemotherapy for small cell lung cancer. 1995, 6 Suppl 5:53-63 Anticancer Drugs
Journal:
Anticancer Drugs
Issue Date:
Oct-1995
URI:
http://hdl.handle.net/10541/107469
PubMed ID:
8845495
Type:
Article
Language:
en
ISSN:
0959-4973
Appears in Collections:
All Christie Publications

Full metadata record

DC FieldValue Language
dc.contributor.authorRanson, Malcolm Ren
dc.contributor.authorThatcher, Nicken
dc.date.accessioned2010-07-12T15:28:04Z-
dc.date.available2010-07-12T15:28:04Z-
dc.date.issued1995-10-
dc.identifier.citationThe importance of dose and schedule in chemotherapy for small cell lung cancer. 1995, 6 Suppl 5:53-63 Anticancer Drugsen
dc.identifier.issn0959-4973-
dc.identifier.pmid8845495-
dc.identifier.urihttp://hdl.handle.net/10541/107469-
dc.description.abstractTo improve the survival outlook for patients with small cell lung cancer a variety of chemotherapy strategies has been adopted. This review focuses on the evidence for schedule dependency, particularly with regard to etoposide, and reviews the use of alternating chemotherapy protocols and weekly regimens in small cell lung cancer treatment. Recent improvements in supportive care, with the use of haemopoietic growth factors and peripheral blood progenitor cells, have led to renewed interest in the concept of dose intensity. Preliminary results of dose intensification in small cell lung cancer are described and future prospects discussed.en
dc.language.isoenen
dc.subjectLung Canceren
dc.subject.meshAntineoplastic Agents-
dc.subject.meshCarcinoma, Small Cell-
dc.subject.meshDrug Administration Schedule-
dc.subject.meshHumans-
dc.subject.meshLung Neoplasms-
dc.subject.meshRandomized Controlled Trials as Topic-
dc.titleThe importance of dose and schedule in chemotherapy for small cell lung cancer.en
dc.typeArticleen
dc.contributor.departmentCRC Department of Medical Oncology, University of Manchester, UK.en
dc.identifier.journalAnticancer Drugsen

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