The slower cellular recovery after higher-LET irradiations, including neutrons, focuses on the quality of DNA breaks.

2.50
Hdl Handle:
http://hdl.handle.net/10541/104729
Title:
The slower cellular recovery after higher-LET irradiations, including neutrons, focuses on the quality of DNA breaks.
Authors:
Hendry, Jolyon H
Abstract:
Data for many biological end points reviewed here indicate that the responsible lesions are not only more severe but also are often more slowly repaired as the LET of the ionizing radiation is increased. This is reflected in high RBE values for end points assayed at long (in contrast to short) times after irradiation, for example, residual injury in normal tissues and carcinogenesis.
Affiliation:
Cancer Research Campaign Department of Radiation Biology, Paterson Institute for Cancer Research, Christie Hospital, Manchester, United Kingdom.
Citation:
The slower cellular recovery after higher-LET irradiations, including neutrons, focuses on the quality of DNA breaks. 1991, 128 (1 Suppl):S111-3 Radiat. Res.
Journal:
Radiation research
Issue Date:
Oct-1991
URI:
http://hdl.handle.net/10541/104729
PubMed ID:
1924735
Type:
Article
Language:
en
ISSN:
0033-7587
Appears in Collections:
All Paterson Institute for Cancer Research

Full metadata record

DC FieldValue Language
dc.contributor.authorHendry, Jolyon Hen
dc.date.accessioned2010-06-11T14:29:15Z-
dc.date.available2010-06-11T14:29:15Z-
dc.date.issued1991-10-
dc.identifier.citationThe slower cellular recovery after higher-LET irradiations, including neutrons, focuses on the quality of DNA breaks. 1991, 128 (1 Suppl):S111-3 Radiat. Res.en
dc.identifier.issn0033-7587-
dc.identifier.pmid1924735-
dc.identifier.urihttp://hdl.handle.net/10541/104729-
dc.description.abstractData for many biological end points reviewed here indicate that the responsible lesions are not only more severe but also are often more slowly repaired as the LET of the ionizing radiation is increased. This is reflected in high RBE values for end points assayed at long (in contrast to short) times after irradiation, for example, residual injury in normal tissues and carcinogenesis.en
dc.language.isoenen
dc.subject.meshAnimals-
dc.subject.meshDNA-
dc.subject.meshDNA Damage-
dc.subject.meshDNA Repair-
dc.subject.meshDNA, Single-Stranded-
dc.subject.meshEnergy Transfer-
dc.subject.meshNeutrons-
dc.subject.meshRadiation Injuries, Experimental-
dc.titleThe slower cellular recovery after higher-LET irradiations, including neutrons, focuses on the quality of DNA breaks.en
dc.typeArticleen
dc.contributor.departmentCancer Research Campaign Department of Radiation Biology, Paterson Institute for Cancer Research, Christie Hospital, Manchester, United Kingdom.en
dc.identifier.journalRadiation researchen
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